Prenatal Developmental Toxicity Study for a Mushroom Mycelia Complex Drink in Rats
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چکیده
منابع مشابه
Prenatal Developmental Toxicity Study of HEA-enriched Cordyceps Cicadae Mycelia in Sprague- Dawley Rats
Background: Cordyceps cicadae (C. cicadae) has been used in traditional medicine and is presently being developed for therapeutic purposes and dietary supplements. One of its effective bioactive ingredients is N-(2-hydroxyethyl) adenosine (HEA), which can exert an analgesic effect by inhibiting neurotransmitter release and can be used to ameliorate moderate to severe pain, including cancer pain...
متن کاملPrenatal and developmental toxicity study of meclizine and caffeine combination in female albino Wistar rats.
Meclizine and caffeine combination is used for the treatment of morning sickness. Both compounds are teratogenic and caffeine is known to possess anti-fertility activity also. The present study was undertaken to evaluate the reproductive toxic effect of meclizine and caffeine combination. Three doses were taken for the study; low dose (LD; meclizine 3.7 mg/kg and caffeine 3 mg/kg) was selected ...
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CONTEXT Glycoside-based standardized fenugreek seed extract (SFSE-G) demonstrated promising efficacy in animal models of immune-inflammatory conditions. AIM The present study was aimed at embryo-fetal development toxicity evaluation of SFSE-G in Wistar rats as per guideline No. 414 of the Organization for Economic Co-operation and Development (OECD). MATERIAL AND METHODS Mated female rats w...
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This study investigated the potential adverse effects of zinc oxide nanoparticles ([ZnO(SM20(+)) NPs] zinc oxide nanoparticles, positively charged, 20 nm) on pregnant dams and embryo-fetal development after maternal exposure over the period of gestational days 5-19 with Sprague-Dawley rats. ZnO(SM20(+)) NPs were administered to pregnant rats by gavage at 0, 100, 200, and 400 mg/kg/day. All dams...
متن کاملDevelopmental toxicity of N-methylaniline following prenatal oral administration in rats.
OBJECTIVES The objective of the study was to assess prenatal toxicity of N-methylaniline (NMA) administered by gavage to pregnant female rats. MATERIAL AND METHODS Pregnant female rats were administered N-methylaniline in corn oil by gavage at daily doses of 0.8 mg/kg of body weight (b.w.), 4 mg/kg b.w., 20 mg/kg b.w. and 100 mg/kg b.w. from implantation (the 5th day post mating) to the day p...
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ژورنال
عنوان ژورنال: Hans Journal of Food and Nutrition Science
سال: 2018
ISSN: 2166-613X,2166-6121
DOI: 10.12677/hjfns.2018.72011